Gravinate, Uses, Contraindications, Side Effects and in Pregnancy

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Gravinate for motion sickness

Uses of Gravinate

Gravinate is produced by Searle which contains dimenhydrinate. It is being used for the prevention and relief of motion sickness and treatment of vertigo, nausea or vomiting associated with: electroshock therapy, anaesthesia and surgery labyrinthine disturbances, radiation sickness and postfenestration syndrome. It is primarily indicated in conditions like dizziness, menieres disease, nausea and vomiting, vertigo, motion sickness and vestibular disorder.

Pharmaceutical

It is well absorbed from the gastrointestinal tract. Concurrent ingestion of food may delay the rate, but not the extent of its absorption and action. It is metabolized in liver. It has high serum protein binding. The onset of action is within ½ to 1 hour.

Contraindications

Hypersensitivity to the active ingredient, epilepsy, infants and children under 5 years of age due to increased susceptibility to anti-cholinergic agents and their effects.

Precautions

Patients should be warned to inform physician of use and report promptly any occurring gastrointestinal disturbances during administration. It should not be administered to children under 5 and patients in advanced age.

Pregnancy and lactation

It should not be used during the first trimester of pregnancy and during breast feeding. It may inhibit lactation due to its anti-cholinergic activity. Excreted amounts in breast milk may cause increased excitability, irritability and sensitization in the breast fed infant.

Side Effects

Signs and symptoms of hypersensitivity: skin rash, stomach upset and pain, weakness, drowsiness, tiredness and blurred vision.

SPECIAL PRECAUTION: Effect on active attention, driving and operation of machinery. This preparation decrease attention and slows down reflexes and psychomotor reactions. Driving and operation of machinery should be avoided during therapy.

Gravinate Syrup For Children

Gravinate Syrup
Compositions Each 4ml contains
Dimenhydrinate bp 12.5mg
Symptoms Vomiting, Motion Sickness, Nausea
Disease (Not Valid) Motion Sickness and Vertigo
Dose According to prescription
Company Searle
Retail Price in Pakistan Rs 40

Gravinate Tablet For Adult

Gravinate Tablet
Compositions Each tablet contains
Dimenhydrinate BP 50mg
Symptoms Vomiting, Motion Sickness, Nausea
Disease (Not Valid) Motion Sickness and Vertigo
Dose According to prescription
Company Searle
Per Tablet Price in Pakistan Rs 1.1

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